منابع مشابه
Immunogenetics of trophoblastic tumours.
The fetus is an allograft foreign to the mother by the hemizygous set of paternal alleles. In a randomly mating population the mother may be incompatible with the fetus at any locus and the chance of incompatibility is increased according to the number of alleles at that locus. The persistence of the normal human fetal allograft is a puzzle that continues to intrigue biologists. The immunobiolo...
متن کاملThe histopathology of trophoblastic tumours.
Two important advances in the last 40 years have had a profound effect on the prognosis of patients with trophoblastic tumours. In the first place the application of gonadotrophin assay, initially by biological methods and then by the more accurate radioimmunological methods, to the diagnostic problems of patients with trophoblastic disease has made their management considerably easier. Secondl...
متن کاملImmunogenetics Human immunogenetics Editorial overview
Charles Larsen trained as a protein chemist and has studied the biophysics of viral membrane fusion. His current interest is the cellular immunology and genetics of the human nonresponse to hepatitis B vaccine. This interest has broadened to include the relationship between MHC genetic structure and autoimmune phenomena. Abbreviations CEH conserved extended haplotype KIR killer immunoglobulin-l...
متن کاملGATA3 expression in gestational trophoblastic tissues and tumours.
AIMS GATA3 is a zinc-finger transcription factor that is important for trophoblast differentiation. GATA3 is sensitive for urothelial and breast carcinomas, but the specificity is low. The aim of this study was to investigate the expression of GATA3 in trophoblast-related tissues and neoplasia. METHODS AND RESULTS GATA3 immunohistochemistry was performed on 33 placentas, one atypical placenta...
متن کاملBasic Immunogenetics
IN recent years there has been rapid progress in the understanding of Hodgkin's disease and improvements in its treatment so that many patients can now be cured. This has not yet been reflected in the attitude of doctors who too often regard the disease with unjustified pessimism and too frequently give treatment which is merely palliative. This book is by one of the pioneers of the present day...
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ژورنال
عنوان ژورنال: Journal of Clinical Pathology
سال: 1976
ISSN: 0021-9746
DOI: 10.1136/jcp.29.suppl_10.132